Figure 6.

Treatment with Bru abolished OECs transplantation induced increase of Nrf2/HO-1 in 2VO-treated rats. A. Latency to reach platform of four groups on the first 5 training days. B. Representative swim traces of the rats in morris water maze test on the fifth day. C. Time spent in the target quadrant of four groups. D, E. Oxidative parameters including MDA and CuZn/Mn-SOD were determined in brain tissues. F. Protein expression of HO-1 and Nrf-2 were determined by western blot. G. Densitometric analysis of relative HO-1 protein expression. H. Densitometric analysis of relative Nrf-2 protein expression. Data were expressed as mean ± SEM (n = 5 per group). *P<0.05 vs. the 2VO group, **P<0.01 vs. the 2VO group, #P<0.05 vs. the 2VO+OECs group, ##P<0.01 vs. the 2VO+OECs group.