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. 2018 Nov 7;9:4650. doi: 10.1038/s41467-018-07106-z

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — Chromosomal loci of the differentially expressed proteins. a Proteins where the expression of at least one treatment is significantly different from the ancestors (t test p < 0.01; n = 1304; 39% of the total detected proteins). b Among these, 351 proteins exhibit a differential response from the control (Dunnett test p < 0.05). These differentially expressed proteins classify into divergent (Friedman test p < 0.1; n = 70) and convergent responses (Friedman test p > = 0.1; n = 232). Both convergent and divergent responses are non-randomly distributed across the chromosomes (chi-square test; p < 0.0001)