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HEH inhibits tumor growth in BT474 breast cancer xenografts. Mice with subcutaneous tumors were i.p. injected with HEH and controls (PBS, HER2 apt) for 4 week. (A) Tumor growth curve. Tumor sizes were measured twice a week with digital calipers (n = 4). (B) Dissected tumors after treatment. (C) Quantitation of dissected tumor size from (B) (n = 4). (D) Body weight were measured and averaged (n = 4). ∗p < 0.05; ∗∗p < 0.005. Data represent the mean ± SEM.
