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| plasma |
brain |
|||||
|---|---|---|---|---|---|---|
| 5 min [%; SD] | 15 min [%; SD] | 45 min [%; SD] | 5 min [%; SD] | 15 min [%; SD] | 45 min [%; SD] | |
| intact tracer | 79.6 ± 2.3 | 49.2 ± 2.0 | 36.6 ± 1.7 | 96.4 ± 6.3 | 96.4 ± 5.2 | >99.9 |
| nonpolar metabolite 1 | 2.6 ± 0.2 | 9.8 ± 0.8 | 10.5 ± 4.8 | 3.6 ± 6.3 | 3.6 ± 5.2 | |
| nonpolar metabolite 2 | 1.8 ± 0.6 | 9.5 ± 1.3 | 7.2 ± 3.0 | |||
| nonpolar metabolite 3 | 11.3 ± 1.1 | 20.9 ± 1.5 | 33.6 ± 0.2 | |||
| polar metabolites | 3.5 ± 0.5 | 5.6 ± 0.9 | 7.3 ± 2.0 | |||
