Table 2. TMZ Drug Loading and Molecular Weight Characterization of Redox-Responsive PolyMPC–TMZ Copolymers D1–D2.
polymer | target TMZ (mol %) | measured TMZa (mol %) | theoretical Mnb (kDa) | Mnc (kDa) | Đc |
---|---|---|---|---|---|
D1 | 15 | 12 | 27.6 | 36.8 | 1.17 |
D2 | 50 | 43 | 31.2 | 39.3 | 1.14 |
Estimated by 1H NMR spectroscopy.
Theoretical Mn determined from percent monomer conversion, as estimated by 1H NMR spectroscopy.
Estimated by GPC eluting with TFE, calibrated against PMMA standards.