Skip to main content
. 2018 Oct 31;9:2519. doi: 10.3389/fimmu.2018.02519

Figure 4.

Figure 4

Flow cytometry of peripheral blood mononuclear cells shows changes in the proportion of CD8+ T cell subsets. (A) Decrease of CD8+ T cells in uveitis compared to healthy controls. Representative patient and control sample. CD3+ cells are gated from live single cells, as is indicated in Figure S1. (B) Decrease in the CD45RO-CD27- TE population. (C) CCR10+ CD8+ TM cells are significantly higher in BU compared to IU. Bars in plots indicate median, error bars indicate interquartile range. P-values between HC and UV are from Wilcoxon rank-sum test, p-values between uveitis subgroups are from Kruskal–Wallis (KW) test with post-hoc Dunn's correction for multiple testing. AU, HLA-B27 associated anterior uveitis; BU, Birdshot uveitis; HC, healthy control; IU, idiopathic intermediate uveitis; Tc, cytotoxic Tcell; Th, Thelper cell; TE, effector Tcells (CD45RO-CD27-); TN, naïve (CD45RO-CD27+); TM, memory (CD45RO+); UV, Combined Uveitis samples.