Table 1.

Drug dosages per dose level

Dose level	Ixazomib orally on days 1, 8, 15 every 4 weeks	Carboplatin i.v. on days 1,8 and 15 every 4 weeks
1	3 mg	AUC 1.5
2	3 mg	AUC 2
3	4 mg	AUC 2
4	4 mg	AUC 2.5

AUC = area under the curve