Table 4.
Organ Weight and BP at the Terminal End Point: C57BL/6 WT Mice Treated With Isoproterenol and Recombinant INSL6 Protein or Vehicle
| Variable | Isoproterenol | ||
|---|---|---|---|
| Vehicle (n=8) | INSL6 (n=9) | P Valuea | |
| BW, g | 29.00±0.5774 | 29.38±0.6529 | 0.6725 |
| HW/TL, mg/mmb | 6.281±0.1688 | 6.104±0.1297 | 0.4130 |
| HW/BW, mg/gb | 4.899±0.1015 | 4.679±0.0729 | 0.0936 |
| LW/TL, mg/mmc | 7.024±0.1883 | 6.319±0.157 | 0.0110 |
| LW/BW, mg/gc | 5.49±0.1737 | 4.842±0.0857 | 0.0034 |
| Systolic BP, mm Hg | 111.6±2.511 | 112.8±4.221 | 0.8163 |
BP indicates blood pressure; BW, body weight; HW, heart weight; INSL6, insulin‐like peptide 6; LW, lung weight; TL, tibia length; WT, wild type.
a
Unpaired t test, 2 tailed.
b
HW is normalized by TL (HW/TL) or BW (HW/BW).
c
LW is normalized by TL (LW/TL) or BW (LW/BW).