Table 3.
HRs (95% CIs) of CHD, Stroke, and Total CVD for Being Physically Active (≥500 kcal/wk) Within Categories of PCE
| Variable | No. of Events | Age‐ and Treatment‐Adjusted HR (95% CI) | Multivariable HR (95% CI)a |
|---|---|---|---|
| CHD | |||
| All women | 458 | 0.57 (0.47–0.68) | 0.64 (0.53–0.77) |
| PCE | |||
| <5% | 189 | 0.75 (0.57–1.01) | 0.78 (0.58–1.05) |
| 5%–<7.5% | 75 | 0.78 (0.49–1.23) | 0.77 (0.48–1.24) |
| 7.5%–<10% | 60 | 0.58 (0.34–0.98) | 0.57 (0.33–0.98) |
| ≥10% | 134 | 0.47 (0.32–0.68) | 0.51 (0.35–0.74) |
| P value for interaction | … | 0.06 | 0.10 |
| Stroke | |||
| All women | 650 | 0.70 (0.60–0.82) | 0.78 (0.66–0.91) |
| PCE | |||
| <5% | 301 | 0.82 (0.65–1.04) | 0.89 (0.70–1.13) |
| 5%–<7.5% | 94 | 0.73 (0.48–1.10) | 0.71 (0.47–1.08) |
| 7.5%–<10% | 86 | 0.91 (0.59–1.39) | 0.91 (0.59–1.41) |
| ≥10% | 169 | 0.60 (0.44–0.82) | 0.59 (0.43–0.82) |
| P value for interaction | … | 0.31 | 0.36 |
| Total CVD | |||
| All women | 1860 | 0.67 (0.61–0.73) | 0.73 (0.66–0.80) |
| PCE | |||
| <5% | 865 | 0.78 (0.68–0.89) | 0.84 (0.73–0.97) |
| 5%–<7.5% | 296 | 0.79 (0.63–1.00) | 0.78 (0.61–0.98) |
| 7.5%–<10% | 223 | 0.68 (0.52–0.89) | 0.68 (0.52–0.90) |
| ≥10% | 476 | 0.64 (0.53–0.77) | 0.64 (0.53–0.78) |
| P value for interaction | … | 0.13 | 0.17 |
CHD indicates coronary heart disease; CI, confidence interval; CVD, cardiovascular disease; HR, hazard ratio; PCE, pooled cohort equation.
a
Adjusted for age; randomized treatment assignment; smoking status; consumption of alcohol, saturated fat, fiber, fruits, and vegetables; menopausal status; postmenopausal hormone use; and parental history of myocardial infarction <60 years of age.