Table 4.
Incidence Density Ratios for Number of Days Hospitalized for Any Cause per Year by Baseline Serum Sodium Category in 25 095a Subjects With Heart Failure With Preserved Ejection Fraction
| Serum Sodium (mmol/L) | Average Number of Days Hospitalized for Any Cause per Person‐Year (95% CI) | Crude IDR (95% CI) | Age‐Adjusted IDR (95% CI) | Multivariable IDR (95% CI) |
|---|---|---|---|---|
| 115.0–134.9 | 7.59 (6.98–8.26) | 1.55 (1.44–1.67) | 1.61 (1.50–1.74) | 1.44 (1.32–1.56) |
| 135.0–137.9 | 5.95 (5.59–6.34) | 1.20 (1.13–1.28) | 1.22 (1.14–1.31) | 1.18 (1.10–1.27) |
| 138.0–140.9 | 5.06 (4.82–5.32) | REF | REF | REF |
| 141.0–143.9 | 5.02 (4.73–5.33) | 1.03 (0.96–1.09) | 1.00 (0.94–1.07) | 1.03 (0.96–1.10) |
| 144.0–160.0 | 5.66 (5.08–6.32) | 1.19 (1.08–1.31) | 1.16 (1.05–1.28) | 1.19 (1.06–1.33) |
Multivariable model was adjusted for age; sex; race; body mass index; heart rate; estimated glomerular filtration rate; serum potassium; average LVEF; use of calcium channel blockers, angiotensin‐converting enzyme inhibitors/angiotensin receptor blockers; and β‐blockers; and history of coronary artery disease, hypertension, hyperlipidemia, atrial fibrillation, chronic obstructive pulmonary disease, diabetes mellitus, and anemia. CI indicates confidence interval; HF, heart failure; IDR, incidence density ratio; LVEF, left ventricular ejection fraction; REF, referent group.
Excludes people who had a hospital stay >180 days.