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. 2018 Oct 31;9:2510. doi: 10.3389/fimmu.2018.02510

Figure 5.

Figure 5

DDCs do not increase activation markers upon cercaria exposure but do show a trend of increased levels of immunoregulatory markers PD-L1 and PD-L2. Immunoregulatory markers PD-L1 and 2 are up regulated in DDCs when exposed to Cercariae but not RA Cercariae (n = 3) (A). PD-L1 expression primarily occurs in CD1a+ DDCs. (n = 3) (B). CD80 and HLA-DR expression in total emigrated HLA-DR+, CD11c+ antigen presenting cells from dermal biopsy at 84 h post exposure to S. mansoni cercariae or water control (n = 7) (C). Mean ± SEM. *p < 0.05.