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. 2017 Dec 20;8(3):866–879. doi: 10.4338/ACI-2017-04-RA-0059

Table 2.

Characteristics of patients and overridden alerts.

Legacy Commercial p-value
Number of medication orders, n 42,097 36,800 N/A
Total # of unique patients admitted to ICU, n 684 783 N/A
Medical ICU, n (%) 247 (36.1) 274 (35.0) 0.655
Neurology ICU, n (%) 232 (33.9) 272 (34.7) 0.741
Surgical ICU, n (%) 205 (30.0) 237 (30.3) 0.901
Number of unique patients with alerts, n (%) 254 (37.1) 706 (90.2) < 0.0001
Total # of overridden alerts, n 1,030 5,535 N/A
Allergy, n (%) 486 (47.2) 697 (12.6) < 0.0001
DDI, n (%) 326 (31.7) 4,566 (82.5) < 0.0001
Geriatric, n (%) 207 (20.1) 4 (0.1) < 0.0001
Renal, n (%) 11 (1.0) 268 (4.8) < 0.0001

DDI = drug-drug interaction; ICU = intensive care unit.