Table 3.

Characteristics of overridden alerts per alert category.

	Legacy	Commercial	p-value
Allergy
Number of unique patient-alerts *	143	221	N/A
Number of unique patients	105	139	N/A
Median # unique alerts per patient †	1.0 (1.0, 1.0)	1.0 (1.0, 2.0)	0.992
Median # alerts per patient (IQR)	3.0 (2.0, 5.0)	3.0 (2.0, 6.0)	0.451
DDI
Number of unique patient-alerts *	148	1390	N/A
Number of unique patients	114	487	N/A
Median # unique alerts per patient †	1.0 (1.0, 1.0)	4.0 (2.0, 6.0)	< 0.0001
Median # alerts per patient (IQR) †	2.0 (1.0, 4.0)	4.0 (2.0, 10.0)	< 0.0001
Geriatric
Number of unique patient-alerts *	113	4	N/A
Number of unique patients	89	4	N/A
Median # unique alerts per patient	1.0 (1.0, 2.0)	1.0 (1.0, 1.0)	0.105
Median # alerts per patient (IQR) †	2.0 (1.0, 3.0)	1.0 (1.0, 1.0)	< 0.0001
Renal
Number of unique patient-alerts *	7	180	N/A
Number of unique patients	7	68	N/A
Median # unique alerts per patient †	1.0 (1.0, 1.0)	2.0 (1.0, 3.5)	< 0.0001
Median # alerts per patient (IQR)	1.0 (1.0, 2.0)	2.5 (1.0, 5.0)	< 0.0001

^* Indicates the number of unique alerts per patient (i.e., a patient with multiple alerts for a penicillin allergy would only count as one).

^† Indicates p-value < 0.05. DDI = drug-drug interaction.