Figure 1. Overall structure of the GABA-A receptor-Fab complex.
a,b, Top and side views of the 3D reconstruction of GABA-A receptor-Fab complex colored by subunit: α1-green, β2-blue, γ2- magenta; Fab-gray, CHS-yellow. Conformation A is shown. c,d, Top and side view of the atomic model, colored as in a. Flumazenil is shown as cyan spheres, GABA as red spheres and CHS and N-linked glycans are modeled as sticks. e, Structure of single β2 subunit.
