Table 3. Performance metrics of markers alone and combination including AUC, sensitivity, specificity and Youden's index (YI).

Markers	AUC	Sensitivity	Specificity	YI
GGT	0.56	0.17	1.00	0.17
LDH	0.67	0.67	0.73	0.39
GSTπ	0.67	0.75	0.64	0.39
TIMP-1	0.67	0.83	0.55	0.38
KIM-1	0.84	0.92	0.73	0.64
Clusterin	0.83	0.67	0.91	0.58
CysC	0.79	0.92	0.55	0.46
Osteopontin	0.81	0.92	0.64	0.55
Cell count	0.52	0.58	0.64	0.22
KIM-1 + clusterin	0.88	1.00	0.73	0.73
KIM-1 + osteopontin	0.88	0.92	0.73	0.64
Clusterin + osteopontin	0.89	0.92	1.00	0.75
KIM-1 + clusterin + osteopontin	0.95	0.75	1.00	0.75