Table 2.
Thrombin generation parameters of thrombomodulin‐modified thrombin generation testing in controls and patients with compensated (CC) or acutely decompensated cirrhosis (AD), or acute‐on‐chronic liver failure (ACLF)
| ETP (nmol/L IIa × min) | Peak (nmol/L IIa) | Lag time (min) | Vel index (nmol/L IIa × min) | |
|---|---|---|---|---|
| Controls | 440.0 (343.4‐639.8) | 122.8 (93.9‐180.3) | 1.67 (1.46‐1.98) | 61.9 (46.3‐96.5) |
| CC | 699.5 (538.5‐819.3) | 184.5 (152.0‐211.3) | 1.67 (1.33‐1.67) | 99.0 (75.8‐111.0) |
| AD | 736.3 (696.2‐882.3)** | 182.3 (173.2‐215.6)** | 1.33 (1.33‐1.63)* | 102.4 (90.3‐112.1)** |
| ACLF | 648.1 (473.3‐743.7) | 124.5 (86.5‐144.6) | 1.92 (1.67‐2.00) | 60.3 (43.4‐75.0) |
Shown are medians (interquartile ranges). *P < .05, **P < .01 vs controls.