Figure 1.
Clinical and subclinical components of NEPAD. No Evidence of Progression defined as: no 12‐week CDP, as measured by the EDSS; no evidence of 12‐week confirmed ≥ 20% progression on hand/arm function as measured by 9HPT; no evidence of 12‐week confirmed ≥ 20% progression on ambulation as measured by the T25FW test. 9HPT = 9‐Hole Peg Test; CDP = confirmed disability progression; EDSS = Expanded Disability Status Scale; Gd+ = gadolinium‐enhancing; MRI = magnetic resonance imaging; NEPAD = no evidence of progression or active disease; T25FW = Timed 25‐Foot Walk.