TABLE 10. Incidence rates* and percentages† of invasive urinary bladder cancer, by demographic and tumor characteristics — United States,§ 2010–2014.
| Demographic characteristic | Total |
Male |
Female |
|||
|---|---|---|---|---|---|---|
| No. | Rate (95% CI) | No. | Rate (95% CI) | No. | Rate (95% CI) | |
|
Total
|
354,478
|
20.5 (20.4–20.6)
|
268,872
|
35.8 (35.7–35.9)
|
85,606
|
8.8 (8.8–8.9)
|
|
Age group at diagnosis (yrs)
| ||||||
| <40 |
3,145 |
0.4 (0.4–0.4) |
2,170 |
0.6 (0.5–0.6) |
975 |
0.3 (0.2–0.3) |
| 40–49 |
10,369 |
4.8 (4.7–4.9) |
7,491 |
6.9 (6.8–7.1) |
2,878 |
2.6 (2.5–2.7) |
| 50–59 |
42,345 |
19.2 (19.1–19.4) |
31,916 |
29.7 (29.4–30.1) |
10,429 |
9.3 (9.1–9.5) |
| 60–69 |
90,204 |
58.4 (58.0–58.8) |
69,828 |
95.2 (94.5–95.9) |
20,376 |
25.1 (24.7–25.4) |
| 70–79 |
108,913 |
125.4 (124.6–126.1) |
84,699 |
217.5 (216.0–218.9) |
24,214 |
50.6 (49.9–51.2) |
| ≥80 |
99,502 |
172.4 (171.3–173.5) |
72,768 |
340.8 (338.3–343.2) |
26,734 |
73.2 (72.3–74.1) |
|
Race
| ||||||
| White |
322,431 |
21.8 (21.7–21.9) |
246,446 |
38.0 (37.8–38.1) |
75,985 |
9.3 (9.2–9.3) |
| Black |
19,647 |
11.7 (11.5–11.9) |
13,174 |
19.5 (19.1–19.9) |
6,473 |
6.6 (6.4–6.8) |
| American Indian/Alaska Native |
1,155 |
9.0 (8.4–9.5) |
849 |
15.3 (14.1–16.4) |
306 |
4.2 (3.7–4.7) |
| Asian/Pacific Islander |
6,084 |
8.5 (8.3–8.7) |
4,558 |
14.9 (14.5–15.4) |
1,526 |
3.8 (3.6–4.0) |
|
Ethnicity¶
| ||||||
| Hispanic |
15,308 |
11.2 (11.0–11.3) |
11,365 |
19.5 (19.1–19.9) |
3,943 |
5.0 (4.9–5.2) |
| Non-Hispanic |
339,122 |
21.3 (21.3–21.4) |
257,478 |
37.2 (37.1–37.4) |
81,644 |
9.2 (9.1–9.2) |
|
County classification
| ||||||
| Metropolitan |
284,262 |
20.4 (20.3–20.4) |
214,733 |
35.7 (35.5–35.9) |
69,529 |
8.8 (8.8–8.9) |
| Nonmetropolitan |
53,332 |
21.0 (20.8–21.1) |
41,193 |
36.2 (35.8–36.6) |
12,139 |
8.8 (8.6–9.0) |
|
Census region
|
|
|
|
|
|
|
| Northeast |
81,032 |
24.3 (24.2–24.5) |
60,232 |
42.5 (42.2–42.9) |
20,800 |
11.0 (10.8–11.1) |
| Midwest |
84,088 |
21.7 (21.6–21.9) |
63,670 |
37.9 (37.6–38.2) |
20,418 |
9.4 (9.3–9.5) |
| South |
121,179 |
18.8 (18.7–18.9) |
92,425 |
33.0 (32.8–33.2) |
28,754 |
8.0 (7.9–8.1) |
| West |
68,179 |
18.7 (18.6–18.9) |
52,545 |
32.5 (32.3–32.8) |
15,634 |
7.8 (7.6–7.9) |
|
Tumor characteristic**
|
No.
|
%
|
No.
|
%
|
No.
|
%
|
|
Total
|
346,522
|
100.0
|
263,415
|
100.0
|
83,107
|
100.0
|
| Histology | ||||||
| Transitional cell carcinoma |
328,814 |
94.9 |
251,579 |
95.5 |
77,235 |
92.9 |
| Squamous cell carcinoma |
5,506 |
1.6 |
3,170 |
1.2 |
2,336 |
2.8 |
| Adenocarcinoma |
3,829 |
1.1 |
2,551 |
1.0 |
1,278 |
1.5 |
| Epithelial carcinoma, NOS |
6,249 |
1.8 |
4,645 |
1.8 |
1,604 |
1.9 |
| All other histologies |
2,124 |
0.6 |
1,470 |
0.6 |
654 |
0.8 |
|
Stage††
| ||||||
| Localized |
296,493 |
85.6 |
227,058 |
86.2 |
69,435 |
83.5 |
| Regional |
25,399 |
7.3 |
18,696 |
7.1 |
6,703 |
8.1 |
| Distant |
14,366 |
4.1 |
10,047 |
3.8 |
4,319 |
5.2 |
| Unknown | 10,264 | 3.0 | 7,614 | 2.9 | 2,650 | 3.2 |
Abbreviations: CI = confidence interval; NOS = not otherwise specified.
* New cases diagnosed per 100,000 persons, age adjusted to the 2000 U.S. standard population.
† New cases diagnosed.
§ Cancer incidence data were compiled from cancer registries that met the data quality criteria for all invasive cancer sites combined, representing approximately 99% of the U.S. population. (Data from Nevada did not meet U.S. Cancer Statistics publication criteria for 2010–2014.)
¶ Ethnicity is not mutually exclusive from race.
** Only includes microscopically confirmed cases; excludes cases identified only through death certificate or autopsy report.
†† Localized: cancer that is confined to the primary site; regional: cancer that has spread directly beyond the primary site or to regional lymph nodes; distant: cancer that has spread to other organs.