TABLE 2. Incidence rates* and percentages† of invasive laryngeal cancer, by demographic and tumor characteristics — United States,§ 2010–2014.
| Demographic characteristic | Total |
Male |
Female |
|||
|---|---|---|---|---|---|---|
| No. | Rate (95% CI) | No. | Rate (95% CI) | No. | Rate (95% CI) | |
|
Total
|
62,479
|
3.5 (3.4–3.5)
|
49,605
|
6.0 (6.0–6.1)
|
12,874
|
1.3 (1.3–1.4)
|
|
Age group at diagnosis (yrs)
| ||||||
| <40 |
563 |
0.1 (0.1–0.1) |
374 |
0.1 (0.1–0.1) |
189 |
0.0 (0.0–0.1) |
| 40–49 |
3,888 |
1.8 (1.7–1.8) |
2,855 |
2.6 (2.5–2.7) |
1,033 |
0.9 (0.9–1.0) |
| 50–59 |
16,028 |
7.3 (7.2–7.5) |
12,437 |
11.7 (11.5–11.9) |
3,591 |
3.2 (3.1–3.3) |
| 60–69 |
20,840 |
13.4 (13.2–13.5) |
16,802 |
22.7 (22.3–23.0) |
4,038 |
4.9 (4.8–5.1) |
| 70–79 |
14,176 |
16.2 (15.9–16.4) |
11,470 |
29.1 (28.6–29.6) |
2,706 |
5.6 (5.4–5.8) |
| ≥80 |
6,984 |
12.2 (12.0–12.5) |
5,667 |
26.5 (25.8–27.2) |
1,317 |
3.7 (3.5–3.9) |
|
Race
| ||||||
| White |
51,997 |
3.4 (3.4–3.5) |
41,239 |
5.9 (5.8–5.9) |
10,758 |
1.4 (1.3–1.4) |
| Black |
8,751 |
4.5 (4.4–4.6) |
6,911 |
8.5 (8.3–8.7) |
1,840 |
1.7 (1.6–1.7) |
| American Indian/Alaska Native |
331 |
2.1 (1.8–2.3) |
260 |
3.6 (3.1–4.1) |
71 |
0.8 (0.6–1.0) |
| Asian/Pacific Islander |
878 |
1.1 (1.1–1.2) |
752 |
2.2 (2.1–2.4) |
126 |
0.3 (0.2–0.3) |
|
Ethnicity¶
| ||||||
| Hispanic |
3,865 |
2.5 (2.4–2.6) |
3,299 |
4.8 (4.7–5.0) |
566 |
0.7 (0.6–0.7) |
| Non-Hispanic |
58,606 |
3.6 (3.5–3.6) |
46,300 |
6.1 (6.1–6.2) |
12,306 |
1.4 (1.4–1.4) |
|
County classification
| ||||||
| Metropolitan |
48,624 |
3.3 (3.3–3.4) |
38,562 |
5.8 (5.7–5.9) |
10,062 |
1.3 (1.3–1.3) |
| Nonmetropolitan |
10,920 |
4.2 (4.2–4.3) |
8,685 |
7.1 (6.9–7.3) |
2,235 |
1.7 (1.6–1.8) |
|
Census region
| ||||||
| Northeast |
11,835 |
3.5 (3.4–3.5) |
9,320 |
6.1 (6.0–6.2) |
2,515 |
1.4 (1.3–1.4) |
| Midwest |
15,154 |
3.8 (3.7–3.9) |
11,845 |
6.4 (6.3–6.5) |
3,309 |
1.6 (1.5–1.6) |
| South |
26,865 |
4.0 (3.9–4.0) |
21,346 |
6.8 (6.8–6.9) |
5,519 |
1.5 (1.5–1.6) |
| West |
8,625 |
2.3 (2.2–2.3) |
7,094 |
4.0 (3.9–4.1) |
1,531 |
0.8 (0.7–0.8) |
|
Tumor characteristic**
|
No.
|
%
|
No.
|
%
|
No.
|
%
|
|
Total
|
60,676
|
100.0
|
48,165
|
100.0
|
12,511
|
100.0
|
|
Histology
| ||||||
| Squamous cell carcinoma |
58,810 |
96.9 |
46,767 |
97.1 |
12,043 |
96.3 |
| Adenocarcinoma |
381 |
0.6 |
238 |
0.5 |
143 |
1.1 |
| Epithelial carcinoma, NOS |
881 |
1.5 |
687 |
1.4 |
194 |
1.6 |
| All other histologies |
604 |
1.0 |
473 |
1.0 |
131 |
1.0 |
|
Stage††
| ||||||
| Localized |
32,534 |
53.6 |
26,646 |
55.3 |
5,888 |
47.1 |
| Regional |
14,640 |
24.1 |
10,608 |
22.0 |
4,032 |
32.2 |
| Distant |
10,702 |
17.6 |
8,632 |
17.9 |
2,070 |
16.5 |
| Unknown | 2,800 | 4.6 | 2,279 | 4.7 | 521 | 4.2 |
Abbreviations: CI = confidence interval; NOS = not otherwise specified.
* New cases diagnosed per 100,000 persons, age adjusted to the 2000 U.S. standard population.
† New cases diagnosed.
§ Cancer incidence data were compiled from cancer registries that met the data quality criteria for all invasive cancer sites combined, representing approximately 99% of the U.S. population. (Data from Nevada did not meet U.S. Cancer Statistics publication criteria for 2010–2014.)
¶ Ethnicity is not mutually exclusive from race.
** Only includes microscopically confirmed cases; excludes cases identified only through death certificate or autopsy report.
†† Localized: cancer that is confined to the primary site; regional: cancer that has spread directly beyond the primary site or to regional lymph nodes; distant: cancer that has spread to other organs.