TABLE 3. Incidence rates* and percentages† of invasive oral cavity and pharyngeal cancers, by demographic and tumor characteristics — United States,§ 2010–2014.
| Demographic characteristic | Total |
Male |
Female |
|||
|---|---|---|---|---|---|---|
| No. | Rate (95% CI) | No. | Rate (95% CI) | No. | Rate (95% CI) | |
|
Total
|
204,537
|
11.5 (11.4–11.5)
|
144,851
|
17.4 (17.3–17.4)
|
59,686
|
6.4 (6.3–6.4)
|
|
Age group at diagnosis (yrs)
| ||||||
| <40 |
7,562 |
1.0 (0.9–1.0) |
4,153 |
1.1 (1.0–1.1) |
3,409 |
0.9 (0.8–0.9) |
| 40–49 |
19,866 |
9.1 (9.0–9.3) |
14,391 |
13.3 (13.1–13.6) |
5,475 |
5.0 (4.9–5.1) |
| 50–59 |
56,098 |
25.8 (25.6–26.0) |
42,834 |
40.3 (40.0–40.7) |
13,264 |
11.9 (11.7–12.1) |
| 60–69 |
60,210 |
38.4 (38.1–38.7) |
45,247 |
60.7 (60.1–61.2) |
14,963 |
18.3 (18.0–18.6) |
| 70–79 |
37,022 |
42.3 (41.8–42.7) |
25,140 |
63.6 (62.8–64.4) |
11,882 |
24.7 (24.3–25.2) |
| ≥80 |
23,779 |
41.3 (40.8–41.8) |
13,086 |
61.2 (60.1–62.3) |
10,693 |
29.4 (28.8–29.9) |
|
Race
| ||||||
| White |
176,221 |
11.8 (11.8–11.9) |
125,496 |
17.8 (17.7–17.9) |
50,725 |
6.5 (6.4–6.5) |
| Black |
18,089 |
9.2 (9.0–9.3) |
12,574 |
14.5 (14.3–14.8) |
5,515 |
5.1 (5.0–5.2) |
| American Indian/Alaska Native |
1,191 |
7.3 (6.8–7.7) |
843 |
10.9 (10.1–11.7) |
348 |
4.1 (3.7–4.6) |
| Asian/Pacific Islander |
6,519 |
7.8 (7.6–8.0) |
4,257 |
11.2 (10.9–11.6) |
2,262 |
5.0 (4.8–5.2) |
|
Ethnicity¶
| ||||||
| Hispanic |
11,854 |
7.1 (6.9–7.2) |
8,096 |
10.5 (10.3–10.8) |
3,758 |
4.2 (4.1–4.3) |
| Non-Hispanic |
192,676 |
12.0 (12.0–12.1) |
136,750 |
18.2 (18.1–18.3) |
55,926 |
6.6 (6.6–6.7) |
|
County classification
| ||||||
| Metropolitan |
163,768 |
11.3 (11.2–11.3) |
115,587 |
17.1 (17.0–17.2) |
48,181 |
6.3 (6.2–6.3) |
| Nonmetropolitan |
31,220 |
12.5 (12.3–12.6) |
22,450 |
18.7 (18.4–18.9) |
8,770 |
6.7 (6.6–6.9) |
|
Census region
| ||||||
| Northeast |
37,358 |
11.1 (11.0–11.3) |
25,665 |
16.6 (16.4–16.8) |
11,693 |
6.5 (6.4–6.6) |
| Midwest |
46,294 |
11.7 (11.6–11.9) |
32,792 |
17.7 (17.5–17.9) |
13,502 |
6.5 (6.4–6.6) |
| South |
80,910 |
12.1 (12.0–12.2) |
58,190 |
18.6 (18.5–18.8) |
22,720 |
6.5 (6.4–6.6) |
| West |
39,975 |
10.4 (10.3–10.6) |
28,204 |
15.5 (15.4–15.7) |
11,771 |
5.9 (5.8–6.0) |
|
Anatomic subsite
| ||||||
| Lip |
10,035 |
0.6 (0.6–0.6) |
7,284 |
0.9 (0.9–1.0) |
2,751 |
0.3 (0.3–0.3) |
| Oral cavity |
99,539 |
5.6 (5.5–5.6) |
66,678 |
7.9 (7.9–8.0) |
32,861 |
3.5 (3.4–3.5) |
| Salivary gland |
21,517 |
1.3 (1.3–1.3) |
12,629 |
1.7 (1.6–1.7) |
8,888 |
1.0 (1.0–1.0) |
| Tonsil |
38,061 |
2.1 (2.1–2.1) |
31,175 |
3.6 (3.5–3.6) |
6,886 |
0.7 (0.7–0.7) |
| Oropharynx |
9,428 |
0.5 (0.5–0.5) |
7,189 |
0.8 (0.8–0.9) |
2,239 |
0.2 (0.2–0.2) |
| Nasopharynx |
14,393 |
0.8 (0.8–0.8) |
10,925 |
1.3 (1.3–1.3) |
3,468 |
0.4 (0.4–0.4) |
| Hypopharynx |
6,004 |
0.3 (0.3–0.3) |
4,700 |
0.6 (0.5–0.6) |
1,304 |
0.1 (0.1–0.1) |
| Other oral cavity and pharynx |
5,560 |
0.3 (0.3–0.3) |
4,271 |
0.5 (0.5–0.5) |
1,289 |
0.1 (0.1–0.1) |
|
Tumor characteristic**
|
No.
|
%
|
No.
|
%
|
No.
|
%
|
|
Total
|
199,496
|
100.0
|
141,383
|
100.0
|
58,113
|
100.0
|
|
Histology
| ||||||
| Squamous cell carcinoma |
171,299 |
85.9 |
126,036 |
89.1 |
45,263 |
77.9 |
| Adenocarcinoma |
7,579 |
3.8 |
4,014 |
2.8 |
3,565 |
6.1 |
| Mucoepidermoid carcinoma |
6,259 |
3.1 |
2,802 |
2.0 |
3,457 |
5.9 |
| Epithelial carcinoma, NOS |
5,711 |
2.9 |
4,094 |
2.9 |
1,617 |
2.8 |
| All other histologies |
8,648 |
4.3 |
4,437 |
3.1 |
4,211 |
7.2 |
|
Stage††
| ||||||
| Localized |
63,275 |
31.7 |
38,268 |
27.1 |
25,007 |
43.0 |
| Regional |
90,347 |
45.3 |
69,275 |
49.0 |
21,072 |
36.3 |
| Distant |
35,439 |
17.8 |
26,741 |
18.9 |
8,698 |
15.0 |
| Unknown | 10,435 | 5.2 | 7,099 | 5.0 | 3,336 | 5.7 |
Abbreviations: CI = confidence interval; NOS = not otherwise specified.
* New cases diagnosed per 100,000 persons, age adjusted to the 2000 U.S. standard population.
† New cases diagnosed.
§ Cancer incidence data were compiled from cancer registries that met the data quality criteria for all invasive cancer sites combined, representing approximately 99% of the U.S. population. (Data from Nevada did not meet U.S. Cancer Statistics publication criteria for 2010–2014.)
¶ Ethnicity is not mutually exclusive from race.
** Only includes microscopically confirmed cases; excludes cases identified only through death certificate or autopsy report.
†† Localized: cancer that is confined to the primary site; regional: cancer that has spread directly beyond the primary site or to regional lymph nodes; distant: cancer that has spread to other organs.