TABLE 4. Incidence rates* and percentages† of invasive esophageal cancer, by demographic and tumor characteristics — United States,§ 2010–2014.
| Demographic characteristic | Total |
Male |
Female |
||||
|---|---|---|---|---|---|---|---|
| No. | Rate (95% CI) | No. | Rate | (95% CI) | No. | Rate (95% CI) | |
|
Total
|
81,608
|
4.6 (4.6–4.6)
|
64,311
|
8.0
|
(7.9–8.0)
|
17,297
|
1.8 (1.8–1.8)
|
|
Age group at diagnosis (yrs)
| |||||||
| <40 |
706 |
0.1 (0.1–0.1) |
562 |
0.2 |
(0.1–0.2) |
144 |
0.0 (0.0–0.0) |
| 40–49 |
3,951 |
1.8 (1.8–1.9) |
3,223 |
3.0 |
(2.9–3.1) |
728 |
0.7 (0.6–0.7) |
| 50–59 |
15,943 |
7.3 (7.1–7.4) |
13,075 |
12.2 |
(12.0–12.4) |
2,868 |
2.6 (2.5–2.7) |
| 60–69 |
25,765 |
16.5 (16.3–16.7) |
21,335 |
28.8 |
(28.4–29.2) |
4,430 |
5.4 (5.3–5.6) |
| 70–79 |
20,982 |
24.0 (23.7–24.3) |
16,480 |
41.9 |
(41.3–42.6) |
4,502 |
9.4 (9.1–9.7) |
| ≥80 |
14,261 |
24.8 (24.4–25.2) |
9,636 |
45.0 |
(44.1–45.9) |
4,625 |
12.6 (12.3–13.0) |
|
Race
| |||||||
| White |
71,002 |
4.7 (4.7–4.8) |
56,735 |
8.2 |
(8.2–8.3) |
14,267 |
1.7 (1.7–1.8) |
| Black |
7,984 |
4.3 (4.2–4.4) |
5,581 |
7.1 |
(6.9–7.3) |
2,403 |
2.3 (2.2–2.4) |
| American Indian/Alaska Native |
460 |
3.2 (2.8–3.5) |
357 |
5.3 |
(4.7–5.9) |
103 |
1.4 (1.1–1.7) |
| Asian/Pacific Islander |
1,659 |
2.2 (2.1–2.3) |
1,257 |
3.7 |
(3.5–3.9) |
402 |
1.0 (0.9–1.1) |
|
Ethnicity¶
| |||||||
| Hispanic |
4,157 |
2.8 (2.7–2.9) |
3,284 |
4.9 |
(4.7–5.1) |
873 |
1.1 (1.0–1.2) |
| Non-Hispanic |
77,446 |
4.8 (4.7–4.8) |
61,025 |
8.3 |
(8.2–8.3) |
16,421 |
1.8 (1.8–1.9) |
|
County classification
| |||||||
| Metropolitan |
64,726 |
4.5 (4.5–4.5) |
50,559 |
7.8 |
(7.7–7.9) |
14,167 |
1.8 (1.8–1.8) |
| Nonmetropolitan |
13,056 |
5.1 (5.0–5.1) |
10,693 |
8.9 |
(8.7–9.1) |
2,363 |
1.7 (1.6–1.8) |
|
Census region
| |||||||
| Northeast |
16,751 |
4.9 (4.9–5.0) |
12,913 |
8.6 |
(8.5–8.8) |
3,838 |
2.0 (1.9–2.1) |
| Midwest |
20,158 |
5.1 (5.0–5.2) |
15,996 |
8.9 |
(8.8–9.1) |
4,162 |
1.9 (1.8–2.0) |
| South |
29,532 |
4.4 (4.4–4.5) |
23,471 |
7.7 |
(7.6–7.8) |
6,061 |
1.7 (1.6–1.7) |
| West |
15,167 |
4.0 (4.0–4.1) |
11,931 |
6.9 |
(6.8–7.0) |
3,236 |
1.6 (1.6–1.7) |
|
Tumor characteristic**
|
No.
|
%
|
No.
|
%
|
No.
|
%
|
|
|
Total
|
77,252
|
100.0
|
61,024
|
100.0
|
16,228
|
100.0
|
|
|
Histology
| |||||||
| Squamous cell carcinoma |
22,900 |
29.6 |
14,768 |
24.2 |
8,132 |
50.1 |
|
| Adenocarcinoma |
50,492 |
65.4 |
43,361 |
71.1 |
7,131 |
43.9 |
|
| Epithelial carcinoma, NOS |
2,853 |
3.7 |
2,173 |
3.6 |
680 |
4.2 |
|
| All other histologies |
1,007 |
1.3 |
722 |
1.2 |
285 |
1.8 |
|
|
Stage††
| |||||||
| Localized |
15,021 |
19.4 |
11,522 |
18.9 |
3,499 |
21.6 |
|
| Regional |
25,437 |
32.9 |
19,992 |
32.8 |
5,445 |
33.6 |
|
| Distant |
28,248 |
36.6 |
23,359 |
38.3 |
4,889 |
30.1 |
|
| Unknown | 8,546 | 11.1 | 6,151 | 10.1 |
2,395 | 14.8 | |
Abbreviations: CI = confidence interval; NOS = not otherwise specified.
* New cases diagnosed per 100,000 persons, age adjusted to the 2000 U.S. standard population.
† New cases diagnosed.
§ Cancer incidence data were compiled from cancer registries that met the data quality criteria for all invasive cancer sites combined, representing approximately 99% of the U.S. population. (Data from Nevada did not meet U.S. Cancer Statistics publication criteria for 2010–2014.)
¶ Ethnicity is not mutually exclusive from race.
** Only includes microscopically confirmed cases; excludes cases identified only through death certificate or autopsy report.
†† Localized: cancer that is confined to the primary site; regional: cancer that has spread directly beyond the primary site or to regional lymph nodes; distant: cancer that has spread to other organs.