Table 3.
Associations between organ damage and cognitive performance (overall cognition composite score)
| cSVD score | LVMI | eGFR | UAE | |||||
|---|---|---|---|---|---|---|---|---|
| B (95% CI) | P | B (95% CI) | P | B (95% CI) | P | B (95% CI) | P | |
| Unadjusted linear regression |
−0.237 (−0.390 to −0.084) |
0.003 |
−0.009 (−0.017 to −0.001) |
0.024 |
0.008 (−0.001 to 0.017) |
0.077 |
−0.001 (−0.005 to 0.003) |
0.574 |
| Corrected for age, sex, DART score |
−0.173 (−0.298 to −0.048) |
0.007 |
−0.008 (−0.014 to −0.002) |
0.010 |
−0.001 (−0.009 to 0.007) |
0.881 |
−0.002 (−0.004 to 0.001) |
0.232 |
| Corrected for age, sex, DART score, and cSVD score | NA | NA |
−0.007 (−0.013 to −0.001) |
0.032 |
−0.002 (−0.010 to 0.006) |
0.624 |
−0.001 (−0.003 to 0.002) |
0.714 |
B, unstandardized regression coefficient; CI, Confidence interval; cSVD, cerebral small vessel disease; DART, Dutch adult reading test; eGFR, estimated glomerular filtration rate; LVMI, left ventricular mass index; NA, not applicable; UAE, urinary albumin excretion.