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. 2018 Aug 29;70(11):1853–1865. doi: 10.1002/art.40556

Figure 5.

Figure 5

Expression of circulating Tfh (cTfh) cell subsets in patients with IgG4‐RD compared to healthy controls. A, Expression of cTfh1 (CXCR3+CCR6−), cTfh2 (CXCR3−CCR6−), and cTfh17 (CXCR3−CCR6+) cells was assessed in peripheral CD4+ T cells from patients with IgG4‐RD and healthy controls and in submandibular gland tissue from patients with IgG4‐RD. B–E, Percentages of circulating CXCR3+CCR6+ T cells (B) as well as cTfh17 (C), cTfh1 (D), and cTfh2 cells (E) were determined in peripheral CD4+ T cells from patients with IgG4‐RD (n = 38) compared to healthy controls (n = 26), and in submandibular gland tissue from patients with IgG4‐RD (n = 4). Symbols represent individual subjects; horizontal lines with bars show the mean ± SD. ** = P < 0.001. See Figure 1 for other definitions.