Figure 1.

miR‐16 is downregulated in oral squamous cell carcinoma (OSCC) tissues and cell lines. (a) The relative expressions of miR‐16 in eighteen OSCC patients and their matched normal tissues were determined by qRT‐PCR. (b) The relative expressions of miR‐16 in five OSCC cell lines and a human immortalized oral epithelial cells (HIOEC) were checked by qRT‐PCR. Data were presented as mean ± standard deviation for three independent experiments. *p < 0.05, **p < 0.01, ***p < 0.001 versus normal tissues or HIOEC cells. miR‐16, microRNA‐16; qRT‐PCR, quantitative reverse transcription polymerase chain reaction