Figure 5.

miR‐16 negatively relates to AKT3 and BCL2L2. Pearson correlation analysis of miR‐16 and AKT3 (a) or BCL2L2 (b) expression in the OSCC patient cohort. The relative expressions of AKT3 (c) or BCL2L2 (d) were detected by qRT‐PCR in the miR‐16 mimic/inhibitor or scramble‐transfected SCC‐25 and CAL‐27 cells. Data were presented as mean ± standard deviation for three independent experiments. *p < 0.05, **p < 0.01, ***p < 0.001 versus the negative control. miR‐16, microRNA‐16; OSCC, oral squamous cell carcinoma; qRT‐PCR, quantitative reverse transcription polymerase chain reaction