Table 5.
Comparison of kidney transplant outcomes by donor type (DBD and DCD) and donor death secondary to ligature asphyxiation
| DBD donors following ligature asphyxiation (n = 294) | All other DBD donors (n = 14 382) | DCD donors following ligature asphyxiation (n = 356) | All other DCD donors (n = 6661) | Unadjusted ratio (95% CI) ligature asphyxiation vs. nonligature asphyxiation | Adjusted ratio (95% CI) ligature asphyxiation vs. nonligature asphyxiation | Adjusted P value | |
|---|---|---|---|---|---|---|---|
| Primary‐nonfunction | 1/262 (0.4%) | 275 /12741 (2.2%) | 8/320 (2.5%) | 157/5899 (2.7%) | OR 0.694 (0.357‐1.351) | OR 0.989 (0.704‐1.388) | .948 |
| Delayed graft function | 40/262 (15.2%) | 2778/12741 (21.8%) | 116/320 (36.3%) | 2377/5899 (40.3%) | OR 0.946 (0.783‐1.142) | OR 1.050 (0.952‐1.160) | .325 |
| 1‐y death censored graft survival | 96.8% | 94.3% | 95.6% | 93.6% | HR 0.638 (0.426‐0.955) | HR 0.851 (0.565‐1.283) | .442 |
| 5‐y death censored graft survival | 92.8% | 86.8% | 92.2% | 86.8% | HR 0.557 (0.403‐0.771) | HR 0.775 (0.564‐1.06) | .115 |
| 1‐y patient survival from transplantation | 97.5% | 96.5% | 97.9% | 95.8% | HR 0.613 (0.361‐1.041) | HR 0.984 (0.585‐1.655) | .951 |
| 5‐y patient survival from transplantation | 91.9% | 89.3% | 92.4% | 86.6% | HR 0.667 (0.478‐0.932) | HR 1.05 (0.757‐1.456) | .772 |
| 1‐y first kidney death censored graft survival (n = 18 059) | 97.8% | 96.5% | 98.0% | 95.7% | HR 0.619 (0.388‐0.987) | HR 0.814 (0.506 1.307) | .269 |
| 5‐y first kidney death censored graft survival (n = 18 059) | 95.2% | 88.4% | 93.5% | 87.3% | HR 0.506 (0.343‐0.745) | HR 0.705 (0483‐1.03) | .07 |
| 12‐mo eGFR (n = 17 846) | 61.4 (46.7‐ 76.6) (n = 238) | 50.4 (38.3‐ 64.8) (n = 11953) | 57.9 (46.2‐ 68.7) (n = 299) | 46.6 (34.9‐59.6) (n = 5350) | PE 9.525 (7.482‐11.567) | PE 0.686 (−1.103‐ 2.476) | .452 |
CI, confidence interval; DBD, donation after brain death; DCD, donation after circulatory death; HR, hazard ratio; OR, odds ratio; PE, parameter estimate.