Table 2.
Relative characteristics of patients with a CD4:CD8 ratio ≥ 1 and < 1, for patients with a viral load < 50 copies/mL (n = 93)
| CD4:CD8 < 1 (n = 35) | CD4:CD8 ≥ 1 (n = 58) | P‐value | |
|---|---|---|---|
| Age (years) [median (IQR)] | 16.3 (14.9–16.7) | 14.8 (12.1–16.8) | 0.03 |
| Sex female [n (%)] | 19 (54) | 35 (60) | 0.56 |
| Ethnicity black African [n (%)] | 27 (77) | 45 (78) | 0.96 |
| Absolute CD4 count (cells/μL) [median (IQR)] | 667 (528–784) | 1033 (704–1373) | < 0.01 |
| Absolute CD8 count (cells/μL) [median (IQR)] | 959 (841–1146) | 703 (510–850) | < 0.01 |
| Nadir CD4 count (cells/μL) [median (IQR)] | 260 (170.5–500.5) | 480 (283–685) | < 0.01 |
| Time suppressed on ART (months) [median (IQR)] | 57 (22–107) | 112 (62.3–139.3) | 0.002 |
| Age at start of ART (months) [median (IQR)] (n = 88) | 113.4 (63.7–148) | 21.1 (4.1–45.8) | < 0.01 |
| CD4:CD8 at start of ART [median (IQR)] (n = 57) | 0.38 (0.19–0.64) | 0.61 (0.35–1.19) | 0.06 |