Table 2.
Test performance of individual IBMP chimeric antigens to diagnose chronic Chagas disease using latent class status as a gold standard
Chimeric antigen | Sensitivity (%) | Specificity (%) | Accuracy |
---|---|---|---|
IBMP-8.1 | 96.4 [93.7–98.0] | 99.6 [97.7–99.9] | 97.8 [96.3–98.8] |
IBMP-8.2 | 93.5 [90.2–95.8] | 99.6 [97.7–99.9] | 96.2 [94.3–97.5] |
IBMP-8.3 | 96.8 [94.1–98.2] | 100.0 [98.5–100.0] | 98.2 [96.7–99.0] |
IBMP-8.4 | 99.4 [97.7–99.8] | 100.0 [98.5–100.0] | 99.6 [98.7–99.9] |
IBMP = Molecular Biology Institute of Paraná. Values in brackets represent 95% confidence interval.