Skip to main content
. 2018 Sep 10;99(5):1234–1238. doi: 10.4269/ajtmh.18-0180

Table 1.

Treatment provided to the patients

Treatment* Aged 12 years or more Aged less than 12 years
Magnesium sulfate (intravenous) Twenty-four milligrams daily into three divided doses Twelve milligrams daily into three divided doses
If no convulsion within 12 hours, then 16 mg into two divided doses If no convulsion within 12 hours, then 8 mg into two divided doses
If no convulsion within 24 hours, then 8 mg single dose If no convulsion within 24 hours, then 4 mg single dose
Then if no convulsion state continues, then finally stop Then if no convulsion state continues, then finally stop
Diazepam (intravenous with infusion) Sixty milligrams daily into three divided doses Thirty milligrams daily into three divided doses
If able to take food by mouth, then 40 mg into two divided doses for 24 hours If able to take food by mouth, then 20 mg into two divided doses for 24 hours
If improvement continues, then 20 mg once daily for 24 hours If improvement continues, then 10 mg once daily for 24 hours
Finally, if improvement continues, then stop Finally, if improvement continues, then stop
Immunotherapy (intramuscular) Human TIG 500 units Human TIG 250 units
TT-containing vaccine, 0.5 mL TT-containing vaccine, 0.5 mL
Antibiotics (intravenous) Metronidazole intravenously 500 mg every 6 hours for 14 days Metronidazole intravenously 250 mg every 6 hours for 14 days
Ceftriaxone 2 gm intravenously daily for 14 days One milligram intravenously daily for 14 days
Fluid (intravenous) One liter 5% dextrose aqua daily during hospital stay 0.5 L 5% dextrose aqua daily up to hospital staying
Two liter dextrose in normal saline daily during hospital staying One liter dextrose in normal saline daily during hospital stay
*

 Those who had no previous immunization history advised to complete a three-dose cycle of tetanus toxoid (TT)- tetanus toxoid immune globuline (TIG).

 Discharged patients also advised to complete their antibiotic schedule.