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. 2018 Nov 7;13(11):e0207083. doi: 10.1371/journal.pone.0207083

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© 2018 Lee, Kable

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Fig 1 — 6 runs of data was simulated with ISI drawn from U(0, 4), and noise std. = 0.8. Single trial estimates were performed with LS-S procedure. Top panels plot the estimated activity levels of each trial for each run. Two trial types are color-coded and their respective run-level means are also shown in color-coded bars to show spurious mean shifts. The horizontal dotted line marks the experiment-wise mean across runs. The bottom panels plot the same data but with run-level mean centering, which essentially subtracts the mean of all trial estimates in a run (shown in black bar) from all the trial estimates within the said run.