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. 2018 Oct 26;14(10):e1007676. doi: 10.1371/journal.pgen.1007676

Fig 4. Zelda putative binding sites in the MS2 cassette.

Fig 4

A) Position weight matrix of the Zelda binding site [34]. The critical positions in the canonical Zelda site CAGGTAG are highlighted in bold. B) The 24 MS2 stem loop repeat corresponds to 12 tandem repetitions of the two MS2 repeats shown. In this sequence, the MS2 loops (red) are separated by either a short (purple) or a long (green) linker. The short linker contains one CAGGTCG sequence which harbors a single but critical mismatch with the canonical Zelda site. The long linker contains one TAGGTAC and one TAGGCAA which harbor respectively two or three permissive (not critical) mismatches with the canonical Zelda site.