Table 3.
ROC analysis results by sensitivity, specificity, predictive values and diagnostic accuracy and area under the ROC
| Diagnostic performance | Parameter | Cut-off value | Sensitivity (%) | Specificity (%) | PPV (%) | NPV (%) | Diagnostic accuracy (95% CI) |
AUC (95% CI) | p |
| Differentiating lymphoma from normal LN | SMI -VI | >15% | 91 | 99 | 96 | 94 | 95 (90–98) | 97 (95–99) | 0.001 |
| Elastography parameters | >17 kPa >2.45 m sn–1 |
96 90 |
100 99 |
100 96 |
99 95 |
99 (96–99) 95 (46–63) |
99 (99–100) 98 (95–100) |
0.001 0.001 |
|
| SI | >65% | 63 | 100 | 100 | 90 | 91 (86–95) | 91 (85–97) | 0.001 | |
| Differentiating lymphadenitis from normal LN | SMI -VI | >11% | 85 | 84 | 85 | 85 | 85 (78–90) | 85 (78–92) | 0.001 |
| Elastography parameters | >2.24 m sn–1 >15 kPa |
25 27 |
97 96 |
82 82 |
73 74 |
74 (66–80) 74 (66–80) |
61 (51–71) 60 (41–61) |
0.01 0.01 |
|
| SI | >55% | 47 | 93 | 78 | 78 | 78 (71–84) | 75 (65–85) | 0.001 | |
| Differentiating lymphoma from lymphadenitis | SMI -VI | >15% | 85 | 81 | 84 | 82 | 83 (79–85) | 82 (80–85) | 0.001 |
| Elastography parameters | >2.45 m sn–1 >17 kPa |
96 96 |
82 81 |
77 76 |
98 97 |
88 (79–99) 87 (78–93) |
91 (0–100) 91 (0–100) |
0.001 0.001 |
|
| SI | >65% | 63 | 70 | 56 | 76 | 68 (57–77) | 72 (64–86) | 0.002 |
AUC, area under the curve; LN, lymph node; NPV, negative predictive value; PPV, positive predictive value; ROC, receiver operating characteristic; SI, shape index; SMI, superb microvascular imaging; VI, vascularity index.