REAGENT or RESOURCE	SOURCE	IDENTIFIER
Antibodies
Gfap – Rabbit polyclonal, 1:5000	Dako/Agilent	Cat# Z0334; RRID:AB_10013482
Gfap- Mouse monoclonal, 1:1000 (Co-stain only)	Novus	Cat# NBP1-05197; RRID:AB_1555288
Bmal1- Rabbit Monoclonal, 1:2000 (IF/IHC only)	Novus	Cat# NB100-2288; RRID:AB_10000794
Bmal1- Rabbit polyclonal, 1:1000 (WB only)	Bethyl	Cat# A302-616A; RRID:AB_10555918
MAP2- Mouse monoclonal, 1:1000	EMD/Milipore	Cat# AB5622; RRID:AB_91939
Ki67- Rat monoclonal, SolA15, 1:500	ThermoFisher	Cat# 14-5698-82; RRID:AB_2016711
NeuN- Mouse monoclonal, 1:1000	EMD/Millipore	Cat# MAB377; RRID:AB_2298772
P42/44 MAPK ERK 1/2- Rabbit monoclonal, 1:1000 (WB)	Cell Signaling Technology	Cat# 9102; RRID:AB_330744
Bacterial and Virus Strains
AAV8-GFAP-eGFP	UNC Viral Vector Core	N/A
AAV8-GFAP-GFP-Cre	UNC Viral Vector Core	N/A
Chemicals, Peptides, and Recombinant Proteins
Lipofectamine RNAiMAX transfection reagent	ThermoFisher/Life	Cat# 13778075
N-acetyl-L-cysteine	Sigma	Cat# A7250
Tamoxifen	Sigma	Cat# T5648
L-Buthionine sulfoxime	Sigma	Cat# 5082280001
Poly-D-lysine hydrobromide	Sigma	Cat# P6407
Critical Commercial Assays
BioGEE Glutathionylation assay kit	ThermoFisher	Cat# G36000
High Capacity RNA-to-cDNA Kit	Applied Biosystems	Cat# 4387406
GSH/GSSG Ratio Detection Assay Kit	Abcam	Cat# ab138881
Taqman Universal PCR Master Mix	Applied Biosystems	Cat# 4304437
PureLink RNA Mini Kit	Ambion/Life	Cat# 12183025
Deposited Data
Agilent 4x44k mouse microarray v2 data from Nestin-Bmal1, Per1;Per2 double mutant, and control cortex at CT 6 and 18.	This paper	ArrayExpress (EMBL-EBI) Accession#: E-MTAB-7151
Experimental Models: Organisms/Strains
B6.Cg-Tg(CAG-cre/Esr1*)5Amc/J (CAG-CreERT2 mice)	Jackson Labs	Cat# 004682
B6;FVB-Tg(Aldh1l1-cre/ERT2)1Khakh/J (Aldh1l1-CreERT2 mice)	Jackson Labs	Cat# 029655
B6.Cg-Tg(Nes-cre)1Kln/J (Nestin-Cre mice)	Jackson Labs	Cat# 003771
B6.129S4(Cg)-Arntltm1Weit/J (Bmal1f/f mice)	Jackson Labs	Cat# 007668
CamKIIalpha iCre BAC (CamK2a-Cre mice)	Casanova et al., 2001	N/A
Oligonucleotides
SMARTpool ON-TARGETplus Arntl siRNA	Dharmacon	Cat# L-040483-01-0005
ON-TARGETplus Non-targeting siRNA1	Dharmacon	Cat# D-001810-02-05
Gfap Taqman Gene expression assay	Applied Biosystems	Mm01253033_m1
Actb Taqman Gene expression assay	Applied Biosystems	Mm02619580_g1
Bmal1 (Arntl) Taqman Gene expression assay	Applied Biosystems	Mm00500223_m1
Aqp4 Taqman Gene expression assay	Applied Biosystems	Mm00802131_m1
Nr1d1 Taqman Gene expression assay	Applied Biosystems	Mm00520708_m1
Serpina3n Taqman Gene expression assay	Applied Biosystems	Mm00776439_m1
S100a6 Taqman Gene expression assay	Applied Biosystems	Mm00771682_g1
Il6 Taqman Gene expression assay	Applied Biosystems	Mm00446190_m1
Il33 Taqman Gene expression assay	Applied Biosystems	Mm00505403_m1
C4b Taqman Gene expression assay	Applied Biosystems	Mm00437893_g1
Cxcl5 Taqman Gene expression assay	Applied Biosystems	Mm00436451_g1
Mmp14 Taqman Gene expression assay	Applied Biosystems	Mm00485054_m1
Timp1 Taqman Gene expression assay	Applied Biosystems	Mm01341361_m1
Dbp Taqman Gene expression assay	Applied Biosystems	Mm00497539_m1
Gsta2 Taqman Gene expression assay	Applied Biosystems	Mm03019257_g1
Gsta4 Taqman Gene expression assay	Applied Biosystems	Mm00494803_m1
Gstt3 Taqman Gene expression assay	Applied Biosystems	Mm00519528_m1
Software and Algorithms
Ingenuity Pathway Analysis	QIAGEN	Build Version: 400896M; Content version 28820210
Imaris	Bitplane	Version 9
Prizm	GraphPad	Version 7
DAVID Bioinformatics Resource	https://david.ncifcrf.gov/	Version 6.8
Fiji	https://fiji.sc/	N/A