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. Author manuscript; available in PMC: 2018 Dec 1.
Published in final edited form as: Expert Rev Neurother. 2017 Oct 30;17(12):1167–1177. doi: 10.1080/14737175.2017.1395700

Figure 1.

Figure 1.

The diagram outlines the key events that occur after ischemic brain injury following 1. thrombosis, 2. energy failure, imbalance of ion homeostasis, acidosis, intracellular calcium overload, neuronal excitotoxicity, 3. inflammatory cell activation and infiltration, 4. glial cell activation and 5. neuronal death with tissue infarction as a final result.