Table 8. AADs for pharmacological cardioversion²⁵⁾ .

Drug	Route	Dosage	Risks
Amiodarone	Oral	Oral 600–800 mg daily in divided doses to a total load of up to 10 g, then 200 mg q.d. as maintenance	Gastrointestinal upset, constipation, bradycardia/AV block, hypotension, QT prolongation, torsades de pointes (rare), phlebitis (IV), increased INR
	IV	150 mg over 10 minutes, then 1 mg/min for 6 hours, then 0.5 mg/min for 18 hours or change to oral dosing
Flecainide	Oral	200–300 mg	Atrial flutter with 1:1 AV conduction, ventricular proarrhythmia, hypotension
Propafenone	Oral	450–600 mg	Atrial flutter with 1:1 AV conduction, ventricular proarrhythmia, hypotension

AAD = antiarrhythmic drug; AV = atrioventricular; INR = international normalized ratio; IV = intravenous; q.d. = once a day or once daily.