Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Nov 1;6:315. doi: 10.3389/fped.2018.00315

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2018 Abballe, Mastronuzzi, Miele, Carai, Besharat, Moretti, De Smaele, Giangaspero, Locatelli, Ferretti and Po.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

NUMB isoforms expression in human MB samples. (A) qRT-PCR analysis showed NUMB isoforms [p66 (left) and p72 (right)] mRNA expression for molecular subgroups of primary MBs (WNT n: 10; SHH n: 25; G3 n: 25; G4 n: 19), adult normal cerebellum (Adult cereb) and fetal normal cerebellum (Fetal cereb). *P-value vs. Adult cereb, *p < 0.05; **p < 0.01; ****p < 0.0001. ° = P vs. Fetal cereb, °p < 0.05. ^§P-value vs. SHH MBs, ^§p < 0.05; ^§§p < 0.01. (B) Pearson's correlation test of p66 vs. p72, in human MB subgroups, to evaluate the link between the expression of NUMB isoforms (r = correlation coefficient; p < 0.05 significance).