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. Author manuscript; available in PMC: 2018 Nov 8.
Published in final edited form as: Structure. 2018 Aug 23;26(11):1431–1439.e6. doi: 10.1016/j.str.2018.07.007

Figure 4. NMR chemical shift induced by co-repressor peptide.

Figure 4.

(A) Differential 2D [1H,15N]-TROSY-HSQC NMR data comparing apo-PPARγ without or with 2 equivalents of NCoR1–3 or SMRT2 corepressor peptide. (B) Fluorescence polarization assay data showing the affinity of PPARγ for NCoR1–3 (240 nM) and SMRT2 (170 nM) are similar. Results are expressed as mean +/− SEM.