Table 2.

Histopathological changes in the buccal mucosa of untreated control and experimental hamsters in each group (n = 10).

Groups/Treatment	Untreated control	DMBA	DMBA + SRA (50 mg/kg bw)	SRA alone (50 mg/kg bw)
Keratosis	–	+++	++	++
Hyperplasia	–	+++	+	+
Dysplasia	–	+++	–	–
SCC	–	+++	–	–

– = No change, + = Mild, ++ = Moderate, +++ = Severe.