TABLE 2.
Occurrence of adverse events during the probiotic and placebo intervention perioda
| Symptom | Severity | No. of events occurring during administration of: |
P value | |
|---|---|---|---|---|
| Probiotic (n = 28) | Placebo (n = 28) | |||
| Abdominal pain | Mild | 1 | 1 | 0.157 |
| Moderate | 0 | 1 | ||
| Allergic reaction | Mild | 0 | 1 | 1.000 |
| Arthralgia | Mild | 1 | 0 | 1.000 |
| Diarrhea | Mild | 1 | 3 | 0.577 |
| Moderate | 1 | 1 | ||
| Gastritis and enterocolitis | Moderate | 1 | 1 | 1.000 |
| GI disorders—other, loose stools | Mild | 4 | 5 | 1.000 |
| Laryngeal inflammation | Moderate | 0 | 1 | 1.000 |
| Myositis | Mild | 0 | 1 | 1.000 |
| Toothache | Mild | 0 | 1 | 1.000 |
a
Values were compared with McNemar tests when only one grade of severity was reported (mild or moderate) and with Wilcoxon signed-rank tests when two grades were reported. GI, gastrointestinal; n, number of subjects.