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. 2018 Sep 18;293(44):17154–17165. doi: 10.1074/jbc.RA118.003055

Figure 3.

Figure 3.

lncRNA GAS8-AS1 and GAS8 induce apoptosis of HepG2 or SMMC7721 cells via sensitizing them to sorafenib. HepG2 or SMMC7721 cells were transfected with expression constructs or siRNAs of GAS8-AS1 or GAS8 first. At the 24th hour after transfection, HCC cells were treated with 1 μmol/liter sorafenib, and apoptosis was determined with a FACSCalibur flow cytometer. All results of the mean of triplicate assays with S.D. (error bars) are presented. *, p < 0.05; **, p < 0.01.