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Effects on gene expressions in immune-related signaling pathways by commonly used drugs.
| NF-κB | STAT | PPAR1γ | ERK | mTOR | AMPK | |
|---|---|---|---|---|---|---|
| H2 receptor antagonist | ||||||
| NSAIDs | ||||||
| Prostaglandin | ||||||
| Norfloxacin | ||||||
| Linezolid | ↓ | |||||
| Macrolide | ↓ | ↓ | ||||
| Antifungal drugs | ||||||
| β2 adrenalin agonist | ||||||
| D2 receptor agonist | ||||||
| ACE inhibitor | ||||||
| ARB | ||||||
| Ca channel blocker | ↓or↑ | |||||
| Digoxin | ||||||
| DPP4 inhibitor | ↑ | |||||
| Biguanide | ↓ | ↑ | ||||
| Statin | ↓ | ↑ | ↑ | |||
| Cannabidiol |
