Table 12.

Association studies of SNPs in SMAD7 gene and CRC.

Population	Reference SNP (rs)	Location	Association	Reference
African American and Caucasian	rs4939827	Intron 3	In women: yes	[166]
	rs4464148	Intron 3	Yes
Caucasian	rs12953717	Intron 3	Yes	[167]
	rs4939827	Intron 3	Yes
	rs4464148	Intron 3	No
Swedish	rs4939827	Intron 3	Yes	[168]
European	rs4464148	Intron 3	Yes	[169]
	rs4939827	Intron 3	No
Chinese	rs4939827	Intron 3	No	[170]
	rs12953717	Intron 3	Yes
	rs4464148	Intron 3	No
African American	rs4939827	Intron 3	Yes	[171]
Chinese	rs4939827	Intron 3	Yes	[76]
Romanian	rs4939827	Intron 3	CRC vs control: no	[172]
			Rectal vs colon cancer: yes
Caucasian	rs4939827	Intron 3	Yes	[173]
Croatian	rs4939827	Intron 3	Yes	[77]
Italian	rs4939827	Intron 3	Yes	[174]
Korean	rs4939827	Intron 3	Yes	[175]
Spanish	rs4939827	Intron 3	Yes	[176]
French	rs4939827	Intron 3	Yes	[177]
	rs58920878	Intron 3	Yes