Table 2.

Melatonin in microorganisms and invertebrates.

Organism	Strategy for Detection	Original Reference(s)
EUBACTERIA
Rhodospirilluym rubrum	RIA	Manchester et al. (1995) [45]
Erythrobacter longus	RIA	Tilden et al. (1997) [83]
Bacillus sp.	UPLC-MS/MS	Jiao et al. (2016) [84]
Euglena gracilis	HPLC	Balzer et al. (1996) [85]
PROTISTS
Lingulodinium (syn Gonyaulax) polyedra (Dinoflagellate)	HPLC	Poeggeler and Hardeland (1994) [86]
Saccharomyces cerevisiae (Yeast)	HPLC	Sprenger et al. (1999) [87]
Euglena gracilis	HPLC	Pandi-Perumal and Cardinali (2007) [87]
Trypanosoma cruzi	RIA	Macías et al. (1999) [47]
Other Dinoflagellates including: Alexandrium (sp.), Ceratium horridum, Amphidinium carterae, Pyrocystis lunula, Noctiluca scintillans	HPLC/RIA	Data obtained from abstracts or proceedings
Ciliates: Tetrahymena thermophila	HPLC	Kohidai et al. (2003) [88]
LOWER INVERTEBRATES
Dugesia japonica	Biosynthetic enzymes	Itoh et al. (1999) [89]
Caenorhabditis elegans	Biosynthetic enzymes	Migliori et al. (2012) [90]
Lumbricus terrestris	Spectrophotometry	Subaraja and Vanisree (2016) [91]
ARTHROPODA
Locusta migratoria	RIA	Vivien-Roels et al(1984) [49]
Drosophila melanogaster, Periplaneta americana	TLC	Finocchiaro et al. (1988) [92]; Richter et al. (2000) [93]
Musa autumnalis	RIA	Wetterberg et al. (1987) [94]
Daphnia magna	ELISA/IHC	Markowska et al. (2009) [95]
Decapoda: Carcinus maenas, Uca pugilator, Nephrops norvegicus, Procambarus sp., Neohelice granulat, Eriocheir sinensis	RIA/HPLC	Vivien-Roels and Pevet (1993) [96]; Tilden et al. (1997) [97]; Aguzzi et al. (2009) [98]; Farca-Luna et al. (2010) [99]; Maciel et al. (2014) [100]; Yang et al. (2018) [101]
COELENTERATES
Renilla koellikeri	RIA	Mechawar and Anctil (1997) [102]
MOLLUSCA
Aplysia californica	HPLC	Abran et al. (1994) [103]
Sepia officinalis	RIA	Vivien-Roels and Pevet (1986) [52]