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Suggested mechanism of action of morusin in MDI-stimulated 3T3-L1 cells and primary adipocytes. In this scheme, (A) anti-lipogenic effects of morusin are thought to be exerted via the inhibition of adipogenic transcription factors and lipogenic proteins, recovery of G0/G1 arrest in cell cycle, and the regulation of the MAPK signaling pathway. (B) Anti-lipolytic effects of morusin are thought to stimulate the activation of lipolytic proteins.
