Figure 5.

In vivo photobleaching of the conjugates: HPPH-CD 8, HPPH₂-CD 9, HPPH-Cypate 10 and HPPH₂-Cypate 11 occurred in the order of 9 > 8 > 11 > 10. There were no photodynamic therapy (PDT) cures upon assessment of the tumor response (the tumors were irradiated with light (Figure 4) at 24 h post-injection). The tumor growth was measured daily, when the tumors reached to a volume of >400 mm³, the mice were euthanized following the approved IACUC protocol. Control: The tumored mice were intravenously (i.v.) injected with the PS but the tumors were not exposed to light.