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Docking simulation of compound 1c and kojic acid with tyrosinase and pharmacophore analysis. Docking simulation results between compound 1c and kojic acid toward mushroom tyrosinase (A). Pharmacophore results for 1c (B) and kojic acid (C) obtained using LigandScout 3.1.2 showing hydrogen-bonding (green arrow), π-π stacking (violet arrow) and hydrophobic (yellow) interactions.
