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The molecular mechanism of PHD association with nucleic acid. Residues determined to be important for binding nucleic acid as mapped by NMR spectroscopy and/or mutagenesis are shown as cyan sticks on a ribbon representation of the BRPF2 PHD2 structure (PDBID 2LQ6). Corresponding representation of the electrostatic surface (determined using the APBS plug-in in pymol) is shown in two orientations.
