Figure 1.

Chemical structure of thioridazine (a), a neuroleptic drug containing a phenothiazine scaffold (a); as well as effective local anesthetics (b) lidocaine (xylocaine); and (c) dibucaine (cinchocaine). All these compounds showed notable in vitro efficiency against some mycobacterial strains [5,6,7,8,9,10,11,12]. Structural fragments of dibucaine were color-coded as follows: a lipophilic moiety (a dark green framework), polar group (orange), connecting hydrocarbon chain (gray) and salt-forming (basic) group (dark red), respectively.