Skip to main content
. 2018 Sep 28;23(10):2493. doi: 10.3390/molecules23102493

Table 2.

Retention times tr (RP-HPLC) and lipophilicity indices log k (RP-HPLC) of the compounds 1ap estimated in the mobile phases with a various volume ratio (v/v) of a methanol (MeOH) organic modifier and water.

Comp. Mobile Phase MeOH/Water (v/v)
80:20 85:15 90:10 95:5 Pure MeOH
tr (min) log k tr (min) log k tr (min) log k tr (min) log k tr (min) log k
1a 13.883 0.7165 10.694 0.5756 7.830 0.3958 5.766 0.2008 4.224 −0.0403
1b 17.200 0.8254 12.647 0.6656 9.449 0.5064 6.514 0.2841 4.526 0.0203
1c 25.694 1.0206 16.950 0.8162 11.292 0.6053 7.431 0.3683 5.246 0.1287
1d 31.000 1.1092 19.600 0.8882 13.553 0.7022 7.892 0.4052 5.385 0.1573
1e 10.330 0.5584 6.917 0.3183 5.400 0.1478 3.822 −0.1454 3.329 −0.2956
1f 12.400 0.6574 9.200 0.4911 6.280 0.2546 4.022 −0.0941 3.340 −0.2913
1g 17.200 0.8254 11.402 0.6104 7.483 0.3679 5.153 0.1182 3.583 −0.2067
1h 22.003 0.9521 13.701 0.7159 8.532 0.4565 5.788 0.2092 3.556 −0.2153
1i 24.020 0.9881 16.917 0.8153 11.691 0.6240 7.765 0.3954 5.127 0.1205
1j 29.525 1.0863 20.021 0.8981 13.060 0.6828 8.520 0.4509 5.295 0.1449
1k 47.108 1.3023 27.001 1.0424 16.533 0.8038 9.641 0.5221 6.938 0.3303
1l 70.012 1.4831 38.800 1.2152 22.636 0.9619 11.670 0.6271 7.756 0.3996
1m 15.731 0.7805 9.218 0.4922 6.420 0.2695 4.685 0.0424 3.519 −0.2275
1n 22.183 0.9502 12.370 0.6542 8.156 0.4205 4.995 0.0941 3.947 −0.1047
1o 29.174 1.0807 13.651 0.7059 9.634 0.5174 5.095 0.1095 4.127 −0.0618
1p 33.719 1.1484 17.129 0.8215 11.332 0.6072 5.801 0.2051 3.925 −0.1102