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Optimization of (A) bovine serum albumin (BSA) and (B) polyethylene glycol hexadecyl ether (Brij58) concentration in incubation with human (HLM) and rat liver microsomes (RLM). Each point represents the mean of zidovudine glucuronides (ZDVG) formation rate ± standard deviation (SD) for triplicates (n = 3).
